93ISOLATION AND CHARACTERIZATION OF AN ANTI ULCER COMPOUND FROM MURRYA KOENIGII (LINN.) SPRENG WETTST LEAVESA compound was isolated from Murrya koenigii (Linn.) Spreng Wettst by solvent extraction, acid hydrolysis, chromatography followed by crystallization. The compound could exert anti-ulcer activity against ethanol induced gastric ulcer and cysteamine induced duodenal ulcer in albino rats. Infra-red spectroscopy, mass spectroscopy and nuclear magnetic resonance studies revealed that the isolated compound was chemically 1,3,5-trihydroxy-7-methylanthracene-9,10-dionedr_pkmitra@rediffmail.comResearch612016Murrya koenigii (Linn.) Spreng Wettst,Anti thiamine effect,Seasonal variationPrasanta Kumar Mitra,Tanaya Ghosh,Prasenjit Mitra,Chandan Sarkar,Sumanta Gupta,Basudeb BasuDepartment of Medical Biotechnology, Sikkim Manipal University, Sikkim Manipal Institute of Medical Sciences, Gangtok, Sikkim, India.,Department of Medical Biotechnology, Sikkim Manipal University, Sikkim Manipal Institute of Medical Sciences, Gangtok, Sikkim, India.,Department of Biochemistry, Sikkim Manipal University, Sikkim Manipal Institute of Medical Sciences, Gangtok, Sikkim, India, Department of Biochemistry, Calcutta Medical College, Kolkata, West Bengal, India.,Department of Chemistry, University of North Bengal, Raja Rammohanpur 734430 Siliguri,West Bengal, India.,Department of Chemistry, University of North Bengal, Raja Rammohanpur 734430 Siliguri,West Bengal, India.