209CAPILLARY ELECTROPHORESIS IN PHARMACEUTICAL RESEARCH: SCOPE AND LIMITATIONSCapillary Electrophoresis (CE) is now among the powerful and multifunctional techniques of experimental study in the pharmaceutical sector that possess resolutive capabilities and efficiency in segregating a wide variety of analytes such as small molecules, peptides, proteins, and nucleic acids. Its working principle is founded on the electrophoretic mobility and electroosmotic flow to achieve appropriate separations and therefore it is appropriate in impurity profiling, chiral drugs enantiomeric separation and bioanalytical studies. CE-MS combines the sensitivity and molecular characterization of CE and, therefore, complex biological samples can be studied in detail. The weaknesses of CE are that it has lower reproducibility and sensitivity compared to other methods such as LC and GC as well as complicated matrices. It is expected that its application will continue to grow in the future through the introduction of the miniaturized form of the CE systems and the addition of AI and automation, making it a valuable tool in a pharmaceutical laboratory of todayVedavarshan19@gmail.comResearch1612026Capillary Electrophoresis, Pharmaceutical Research, Enantiomeric Separation, Mass Spectrometry, BioanalysisVeda Varshan M.P*, Dr. Purushothaman M, Dr. Akila C.RKLR Pharmacy College, Paloncha, Telangana, India.