204A PROSPECTIVE STUDY ON CLINICAL PROFILES AND DEMOGRAPHIC IN PATIENTS WITH SCHIZOPHRENIA AND DEPRESSION To compare socio demographic and clinical profiles of patients with schizophrenia and depression. Objectives: The main objective is to compare clinical and socio demographic profiles in schizophrenia and depression patients. Methods: This is a Prospective cross- sectional observational study, 60 schizophrenia patients as well as 60 depression patients attending psychiatry department of Government general hospital included in this study. The study begins with these lection of patients based on inclusion and exclusion criteria. Then both the patients analyzed for socio demographic and clinical profiles. The severity of the schizophrenia and depression were assessed using the PANSS and Ham-D scales respectively. Results: In this study, among schizophrenia male (56.6%) were predominant and among depression, female (55%) were predominant. Both schizophrenia and depressive patients were equally promote same age groups (30-39).Most of the subjects were married 103 (85.8%), had primary education 62 (51.67%) and were employed 68 (57%). Socio-economic status among the schizophrenia and depression patients were compared (P value= 0.0209). Most of the patients were lower middle class 92(77%).Family history was present in the total of 27 (22.5%) patients. Clinical profiles are compared between the schizophrenia and depression patients (P value=0.015). Most of the schizophrenia patients 22 (37%) has moderate type and most of the depression patients 31 (57%) has severe depression. Conclusion: This study concludes that socio demographic and clinical profiles must be considered in the clinical setting to evaluate suicidal tendencies, family history and other comorbidities in schizophrenia and depression patients.jothies82@gmail.comResearch1512025Schizophrenia, Depression, PANSS, Ham-D, clinical profileShaqulain Reza MD, Adepu Rajani, Are Jayasri, Jeevana K, Jothieswari DhamotharanSri Venkateswara College of Pharmacy, RVS Nagar, Tirupati main Road, Chittoor, Andhra Pradesh – 517 127, India