111REVIEW ON META ANALYSIS OF THERAPEUTIC DRUG MONITORING – A PHARMACOECONOMIC PERSPECTIVETherapeutic drug monitoring (TDM) has been used to individualize drug therapy since the early 1970s. In addition, application of pharmacokinetic principles as part of TDM has been used to assess drug behavior. The aim of TDM is to optimize pharmacotherapy by maximizing therapeutic efficacy, while minimizing adverse events, in those instances where the blood concentration of the drug is a better predictor of the desired effect(s) than the dose. The Cochrane database and Medline were searched. References identified by this approach were then searched manually for relevant articles. Very few studies have been performed that document the cost-effectiveness of TDM.ranampharm@gmail.comReview722017TDM,Cost effective analysis,Cost minimization analysisRanakishor Pelluri,Katta Amulya,Keluth Bhavani,Mantri Satyavathi,Kali Jesus Keerthi,Arumalla Mereena,P.SrinivasababuDepartment of Pharmacy Practice, Vignan Pharmacy College, Vadlamudi, Guntur-522213. Andhra Pradesh- India.,Department of Pharmacy Practice, Vignan Pharmacy College, Vadlamudi, Guntur-522213. Andhra Pradesh- India.,Department of Pharmacy Practice, Vignan Pharmacy College, Vadlamudi, Guntur-522213. Andhra Pradesh- India.,Department of Pharmacy Practice, Vignan Pharmacy College, Vadlamudi, Guntur-522213. Andhra Pradesh- India.,Department of Pharmacy Practice, Vignan Pharmacy College, Vadlamudi, Guntur-522213. Andhra Pradesh- India.,Department of Pharmacy Practice, Vignan Pharmacy College, Vadlamudi, Guntur-522213. Andhra Pradesh- India.,Department of Pharmacy Practice, Vignan Pharmacy College, Vadlamudi, Guntur-522213. Andhra Pradesh- India.